从生存数据的其他信息估计HR值

场景1:根据中位生存时间及事件数计算HR及其置信区间[1, 2]
组1的中位生存时间
组1的事件发生数
组2的中位生存时间
组2的事件发生数
置信水平
场景2:根据HR值及Log-rank的P值计算HR的置信区间[3,4]
风险比(HR)值
Log-rank检验中的P值
置信水平
场景3:根据事件数和随访时间估计HR值[5]
组1的事件发生数 组1的随访人年数
组2的事件发生数 组2的随访人年数

参考文献:

[1] Cortés J, González JA, Campbell MJ, Cobo E. A hazard ratio was estimated by a ratio of median survival times, but with considerable uncertainty. J Clin Epidemiol. 2014 Oct;67(10):1172-7.
[2] https://www.graphpad.com/support/faq/the-confidence-interval-for-the-ratio-of-median-survival-times/
[3] https://www.bmj.com/content/suppl/2007/01/22/bmj.39063.689375.55.dc1/fdetails.pdf
[4] Gillies CL, Abrams KR, Lambert PC, Cooper NJ, Sutton AJ, Hsu RT, Khunti K. Pharmacological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance: systematic review and meta-analysis. BMJ. 2007 Feb 10;334(7588):299.
[5] Bender, R., Beckmann, L. Limitations of the incidence density ratio as approximation of the hazard ratio. Trials 20, 485 (2019). https://doi.org/10.1186/s13063-019-3590-2

>