Statistical Methods for Effect Measure Calculation and Conversion


Methodological Framework

Methodological Framework for Effect Measure Conversion and Synthesis

Note: This page provides an overview of the methodological framework for effect measure conversions. For detailed statistical methods and calculations, please refer to the navigation menu on the left.

The methodological framework is divided into two domains: continuous outcomes (blue section) and categorical/time-to-event outcomes (yellow section). When performing cross-domain conversions, rigorous methodological assumptions must be satisfied to ensure validity.

Methodological Implementation Guide

Scenario Methodological Approach Scenario Methodological Approach
1 Click here for mean difference calculations 2 Click here for standardized mean difference calculations
3 Click here for correlation coefficient transformations 4 Click here for standardized mean difference transformations
5 Click here for standardized mean difference to odds ratio conversion 6 Click here for standardized mean difference to risk ratio conversion
7 Click here for odds ratio to risk ratio conversion 8 Click here for hazard ratio to risk ratio conversion
9 Calculate risk difference using control group incidence (P) and the formula: RD = RR × P - P 10 Calculate risk ratio using control group incidence (P) and the formula: RR = (RD + P) / P
11 Click here for number needed to treat calculations 12 Click here for mean ratio calculations
13 Click here for pre-post design standardized mean difference calculations